Figure Legends:
Legend to Fig 1
Simultaneous computation of biplane left atrial volume and strain
(reservoir, conduit and booster strain) using the 2D strain software on
images sampled at >60 Hz. Data obtained using the 3-click
method (the 2 basal segments and at the roof of the atrium)
Legend to Fig 2
Application of indices of myocardial work in different phenotypes and
grades of aortic stenosis (AS). Left panel: Low flow low gradient
phenotype of severe AS with poor GWE, very low LV-GLS, and very high
global wasted work, necessitating emergent referral for valve
replacement. In comparison, a patient with moderate AS with preserved
global work efficiency (GWE) (upper right) may have a delayed follow up
while the patient in the lower right panel with reduced global wasted
work (GWW), would require a follow up echo sooner than the one with
preserved GWE.
Legend to Fig 3
Aortic valve area estimation using indices of myocardial work.
Parameters included in the model are LVEF%, LV-GLS%, global work
efficiency (GWE), global wasted work (GWW), global work index (GWI), and
global constructive work (GCW). Significant p-values are in red.
Legend to Fig 4
Left ventricular longitudinal strain with apical sparing pattern in
cardiac amyloidosis. The photo collage has been created just by 3-
clicking the apical 3-chamber cine-loops. The AI based software searches
the 2 other apical loops to compute the Bull´s eye with” cherry on the
top” without any more human aid on the 2D spacetime with the LV in
motion.
Legend to Fig 5
Myocardial work efficiency and the apical sparing strain: the differing
pressure strain loops in different apical segments (the green pressure
strain loops in panels B, C, and D) may suggest that the preserved
apical strain may not be homogeneously distributed. Fig A is the global
pressure strain loop in red. Bar diagrams: the green represents
constructive work; blue represents wasted work. Pathophysiological
significance of such heterogeneity is currently unknown.
Legend to Figures 6.
A patient with sigmoid type hypertrophic cardiomyopathy. On the right
side a Bull´s eye plot, created by tracking 3 apical loops, shows
regional strain gradients. On the left side myocardial work index
showing a distorted and truncated pressure strain loop, suggesting a
stiff left ventricle with low global strain and low work efficiency.
Legend to Fig 7
Fig 7. 2 D strain imaging of the right ventricle. Applying a ”3-click”
method that is by placing the cursor at the two basal and the third at
the apical segment, the software simultaneously generates TAPSE, FAC%
and global strain in no time, thereby facilitating an accurate
assessment of RV systolic function.