DISCUSSION
The rarity of Waldmann’s Disease in adulthood and its association with
other significant medical conditions pose diagnostic challenges. The
distinct endoscopic and histological findings, coupled with scintigraphy
results, contribute to a comprehensive understanding of this complex
case. Currently, the sensitivity and negative predictive value of HSA
scintigraphy labeled with 99m Tc make it superior to Alpha 1 antitrypsin
clearance (AATC) in the diagnosis of protein-losing enteropathy (PLE).
In view of the easy application, lack of adverse effects, wide
availability and rapid results, We recommend 99m Tc-labeled HSA
scintigraphy as a method initial diagnostic tool for patients with PLE.
Finally, it is necessary to integrate clinical evaluation, endoscopic,
histological and radiological characteristics, to make an accurate
diagnosis of PLE. case4,5. Differential diagnoses and
management considerations are discussed.