Legends:
Figure 1 : Study selection process flow diagram.
Figure 2: Improvement opportunities - a proposed chain of initiatives based on the review of studies in the countries pointed in the map (Jordan, India, Kenya, Lebanon, Brazil, Nigeria, Honduras, Ethiopia, Peru) and multinational studies. Act 1: International Partnership : Establishing partnerships with the teleconsultation of specialists, mentoring programs, and financial aid to support the development of local programs. Act 2: Nationally Coordinated Programs: Implementing nationally coordinated programs for public assistance, including centralization of care, financial aid from local governments, and educational initiatives. Act 3: Education and Awareness: Develop educational tools for the medical community and general population to increase awareness of the disease, particularly targeting populations at higher risk. Act 4: Screening Programs:Implementing screening programs focused on populations at higher risk, while also incorporating periodic ocular health evaluation for all children. Future considerations include the integration of smartphone applications and algorithms to enhance screening accuracy. Act 5: Genetic Services: Establishing cost-effective genetic screening services to support early detection and diagnosis.
Table 1 : Summary of included studies.