E. multilocularis infection can cause liver injury.
In order to determine whether E. multiloculari s infection can cause liver damage. we used HE staining method to detect the liver pathological damage. The results showed that the mice in the infection group had obvious lesions in the liver and granulocytes gathered around the lesions compared with control group(Fig 2A). The results of Masson staining showed that there were a large amount of collagen fiber deposition in the liver tissue of mice in the infection group(Fig 2B). In addition, The levels of AST and ALT in the serum of mice in the infection group were significantly higher than those in the control group(Table2 and Fig 2C). This results suggested thatE. multiloculari s parasitism can cause damage to liver tissue.