3.6. The relationship between rs12583006 and pSS susceptibility in random health controls and pSS patients
There were statistical differences in rs12583006 in pSS patients and health controls (Table 2). Because of heterogeneity (Figures 6a, 6b and 6c), the genotype of AA, TA and TT chose the fixed model. For rs12583006, OR values, 95% CIs and P values for each genotype and allele are shown in Table 2. There was a relationship between the genotype of AA and TT in rs12583006 and pSS susceptibility, respectively (OR [95% CI], p-value: TT=0.73[0.54-0.99], p=0.04, TA=1.08[0.79-1.49], p=0.63 and AA=2.55[1.34-4.86], p=0.00) (Table 2, Figures 6a, 6b and 6c).