3.1. Literature search and study characteristics
Seven hundred and thirty-seven items satisfied the search criteria based on the search technique. Other sources did not turn up any new research. Due to duplicate content, two hundred and fifty-eight articles were removed. Four hundred and thirty-eight articles were then removed since they didn’t follow our instructions. Forty-one articles were chosen for thorough publishing assessment. Thirty-eight articles were excluded for a variety of reasons. As a result, three case-control studies from three articles were examined in our study (Figure 1). All of the studies that were included were of high quality.
The relevant studies were published between 2014 and 2022. For one particular study, the size of the sample ranged from 101 to 193 for pSS patients and 137 to 309 for health controls. Athenian, Mexican, and Caucasian Greek ethnicities were represented in the studies. The meta-analysis comprised 646 health controls and 442 pSS patients. The SNPs TNFSF13B were studied. SNPs were found in HWE in the health control group (p>0.05). Table 1 shows the features of each eligible study.