3.6. The relationship between rs12583006 and pSS susceptibility
in random health controls and pSS patients
There were statistical differences in rs12583006 in pSS patients and
health controls (Table 2). Because of heterogeneity (Figures 6a, 6b and
6c), the genotype of AA, TA and TT chose the fixed model. For
rs12583006, OR values, 95% CIs and P values for each genotype and
allele are shown in Table 2. There was a relationship between the
genotype of AA and TT in rs12583006 and pSS susceptibility, respectively
(OR [95% CI], p-value: TT=0.73[0.54-0.99], p=0.04,
TA=1.08[0.79-1.49], p=0.63 and AA=2.55[1.34-4.86], p=0.00)
(Table 2, Figures 6a, 6b and 6c).