A new compact-discrete spatial arrangement is introduced on a “fluorescence@magneto” core-shell nanostructure with a close-packed AIEgen core and a meager magnetic shell. The rational design endows the magneto-AIE nanoparticle (MANP) with “win-win” performances: highly retained fluorescent intensity and remarkedly enhanced magnetic activity. The MANP demonstrates great potential in ultrasensitive point-of-care bacterial infection diagnosis on the immunochromatographic assay platform.

Keywords: fluorescent-magneto, aggregation-induced emission, self-assembly, point-of-care test, bacterial infection diagnosis

Authors: Yu Su^{1, 2}, Xirui Chen^{1, 2}, Huan Huang^{4, 5}, Yuhao Wu^{1, 2}, Xuanang Shen^{1, 2}, Xiangkai Lin^{1, 2}, Kun Sun^{1, 2}, Xiao-Yong Fan^{4, *}, Xiaolin Huang^{1, 2, *} and Yonghua Xiong^{1, 2, 3, *}

Title: Rearranging Fluorescence-Magneto Spatiality for “Win-Win” Dual Functions to Enhance Point-of-Care Diagnosis