Study Age Sex Type of Vascular Anomaly Location of Vascular Anomaly Type of Infection Co-Administered Steroids Sirolimus dose, trough, or target trough Duration of Infection before Death Time after starting sirolimus Antibiotic Prophylaxis
Wang, Z. et al. (2019).29 6 months Male Multifocal KHE with KMP Right shoulder, chest, lung, right axilla, chylothorax N.S. N.S. N.S. N.S. N.S. N.S.
Wang, Y. et al. (2020).30
1 month
Male
KHE with KMP
Right neck
Bacterial vs fungal pneumonia
Steroid wean
0.7 mg/m2/d, q12 hours
8 days
2 weeks
N.S.
Rossler, J. et al. (2021). 18 3 months N.S. Microcystic LM Face Viral pneumonia - metapneumovirus N.S. 6.9 ng/ml 4 days 2 months N.S.
2 years N.S. GLA Lung, bowel, spleen Viral pneumonia and ileitis – adenovirus N.S. 8 ng/ml 6 days 24 months TMP-SMX and PCN
Ying, H. et al. (2018).31 3 months Female KHE with KMP Face Pneumonia – unknown pathogen No 0.1 mg/kg 10 days 2 months No
6 months Male KHE with KMP Forearm Pneumonia – mycoplasma Steroid wean 0.1 mg/kg 11 days 1.5 months N.S.