Study Characteristics
Our initial search yielded 3572 unique articles. Exclusions related to irrelevant content (n=3196), wrong patient population (n=125), infection not mentioned (n=113), wrong study design (n=64), wrong intervention (n=33), or text unavailable in English (n=11) (Figure 1). Thirty remaining studies were evaluated, of which most were case series or retrospective chart reviews (n=17, 57%). Studies were reported from geographically diverse populations, including 11 studies from Europe (37%), 9 studies from China (30%), and 7 studies from North America (24%) (Table 1). See Supplemental Table S1 for full details of each included study.