Results
Patient demographics and lesion site: Hundred and ten patients
were enrolled in this study. The male: female ratio was 1:4 and the
average age of the patients was 63 years old (ranged 33 yo- 93 yo).
Majority of the lesions 54/113 (47.8 %) were located in the T-zone
region (ear, eye, nose, lip, and chin), followed by 39/113 (34.5%) in
the head and neck region (scalp, forehead, cheek, and neck), 14/113
(12.4%) on the extremities (arms, legs, hands, and feet), and only
6/113 (5.3%) on trunk and genitalia.
Histopathology diagnosis of the tissue samples collected(Supplemental Table 1) .
A total of 113 tissues were
collected and imaged with the FF-OCT device. Of which, 95 (84 %) were
positive for tumor including 73 (65%) BCCs, 15 (13%) SCCs, 2
basosquamous cell carcinoma (2%), and 5 others (4%). The most common
BCC sub-type was the nBCC 46 (41%), followed by 43 (38%) infiltrative
BCC (iBCC) or micro-nodular BCC (mnBCC) and the least common subtype was
superficial BCCs (sBCC) 3 (3%). The rest 18/113 tissues (15.9%) were
negative for tumors.