Bioreactor Product Titer Measurement by the A2P2 System
In Figure 8a , biological samples, whether manually acquired or automatically delivered, can be introduced into the autosampler via regular sample vials or the FTV. The autosampler initiates sample aspiration from these sources and carries out the injection into an affinity chromatography column within the column compartment. A spectrophotometric detector, such as a UV detector, then establishes the product titer/concentration by comparing it with known concentration standards.