Colorectal cancer is one of the most prevalent malignancies worldwide,
and long-term chronic colitis is considered to be an important factor in
the etiological study of colorectal cancer. As an emerging detection
technology, the non-invasive, non-ionizing, and fingerprint
spectroscopic features of terahertz technology have tremendous
application prospects in disease diagnosis. Therefore, this study aims
to explore the value of terahertz technology in colitis-related cancers
by constructing an inflammation-associated mouse colorectal cancer
model. In this paper, we found that the terahertz spectroscopy technique
can effectively distinguish colitis-associated cancer from normal
tissue, and for the first time, we searched that 1.8 THz may be the best
terahertz frequency for diagnosing colorectal cancer in mice, suggesting
that we can use the terahertz technique for rapid diagnosis of
colorectal cancer histopathology.