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\begin{document}

\title{Amendments of weld formation in human skin laser soldering}



\author[1]{Dmitrii Ryabkin}%
\author[2]{Igor Meglinski}%
\author[1]{Alexander Yu. Gerasimenko}%
\affil[1]{Nacional'nyj issledovatel'skij universitet Moskovskij institut elektronnoj tehniki Fakul'tet Intellektual'nyh tehniceskih sistem}%
\affil[2]{Pervyj Moskovskij gosudarstvennyj medicinskij universitet imeni I M Secenova}%


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  \date{June 18, 2024}


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\begin{abstract}
A computational modeling is employed for quantitative assessment of weld
formation and area of tissue temperature necrosis during the human skin
laser soldering. The evaluation is carried out depending on the
components composition of using solders, including bovine serum albumin
(BSA), indocyanine green (ICG), and carbon nanotubes (CNT), as well as
the angle of incidence of laser light and its pulse duration. The
influence of CNT on the change of thermodynamic characteristics of
albumin denaturation and the rate of formation of the laser weld is
investigated. The obtained results suggest to limit the duration of
laser light pulse by temperature relaxation time to minimize transfer of
thermal energy to reduce the heating of human skin tissues. The
developed model has a great potential for further optimization of laser
soldering of biological tissues technology with greater efficiency in
minimizing the weld area.%
\end{abstract}%



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