Polio vaccines
Some brands of oral Polio vaccine (Sabin) contain alpha-lactalbumin and allergic reactions have been historically reported in four patients with a history of cow’s milk allergy41, nevertheless the majority of milk allergic children receive these vaccines uneventfully suggesting that alpha-lactalbumin is not present in a quantity large enough to elicit a reaction. No special precautions are required when vaccinating milk-allergic patients1.
Traces of Aminoglycosides (Streptomycin, Neomycin and/or Polimixin B) could be contained in inactivated Polio vaccines, that should not be administered to individuals who experienced anaphylaxis to such components, while there are no contraindications in patients who refer allergic contact dermatitis to aminoglycosides or Polimixin B1.