Acknowledgements
The authors would like to thank Pavel Dagorov and his workshop team
(FHNW) for hollow fiber filter modification and Sebastian Schneider and
Silvia Pavone (FHNW) for supporting experimental work on perfusion
processes. The authors also thank the entire Levitronix team for
support, especially Knut Kuss for valuable input. Dominik Schieman, Paul
Niepold and David Garcia (Novartis) kindly sponsored the manufacturing
scale filter module. Moreover, the authors would like to acknowledge
specifically the Bioprocess Sciences (BPS) team of Merck Serono SA (an
affiliate of Merck KGaA) for material and analytical support and for
valuable discussions and support throughout the project, especially
Alexandre Châtelin and the analytical team.