Supplemental Materials
Figure S1 Mapping nonsynonymous/synonymous within CDSs and variations in intergenic regions to metabolism pathways by iPATH.
Figure S2 Transcription coverage after mapping all raw RNA reads to the genome.
Figure S3 Visualization of differences in central carbon metabolism at transcription level.
Figure S4 Comparison of energy level in E3 relative to NRRL23338.
Table S1 Repeated sequences in E3
Table S2 All SNP in E3 with respect to NRRL23338
Table S3 Hierarchical clustering of other key subgroups of genes rather than genes in BGCs
Table S4 Large fragment deletion in E3
Table S5 CDSs with low transcriptional coverage
Table S6 Regulator genes with significant expressional change at 10 h
Table S7 Strains and plasmids used in this study
Table S8 Primers used in this study