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\begin{document}

\title{Predictive role of FAR ratio in Covid-19 patients}



\author[1]{Deniz Çekiç}%
\author[1]{Mehmet Emir Arman}%
\author[2]{Ahmed Cihad  Genç}%
\author[3]{Kubilay İşsever}%
\author[4]{ilhan yıldırım}%
\author[5]{Ahmed Bilal  Genc}%
\author[6]{Hamad  Dheir}%
\author[6]{Selcuk Yaylaci}%
\affil[1]{Sakarya Universitesi Tip Fakultesi}%
\affil[2]{Sakarya Training and Research Hospital}%
\affil[3]{Affiliation not available}%
\affil[4]{İLHAN YILDIRIM}%
\affil[5]{Sakarya Universitesi}%
\affil[6]{Sakarya University}%


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  \date{June 18, 2024}


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\begin{abstract}
Objective: No effective treatment has yet been found for SARS-cov-2,
which caused a pandemic outbreak in 2019. It is crucial to detect the
progression of Covid-19 in patients as early as possible. Fibrinogen to
albumin ratio (FAR) has been used as a new inflammatory marker. We aimed
to find out whether the use of the FAR ratio as a predictor of mortality
in Covid-19 patients provides clinical benefit. Materials and Methods:
Data from 590 patients with Covid-19 from 15/03/2020 to 15/01/2021 in
medicine wards and intensive care units (ICU) were retrospectively
analyzed. Demographic data and other laboratory markers were collected
from the electronic medical records. Relationship between FAR ratio was
investigated between patients in the survivor/non-survivor patients.
Findings: The mean FAR levels in patients who were non survivor was
24.44\selectlanguage{ngerman}±30.3 (n:272 and 11.29±6.29 (n:275) (p:0.000) in patients survivor
COVID-19 infection. In ROC curve for FAR, the threshold FAR that may
pose a risk for mortality was determined as 13.84 ((AUC:
0.808(0.771-0.844)); 74.9\% Sensitivity, 74.6\% Specificity; p:0.000 )).
Result: As a result of this study, increased FAR were found to be
important markers in determining the mortality levels in Covid-19
patients. What is already known about FAR ratio: The fibrinogen albumin
ratio is a value that has been used to determine the prognosis,
especially in malignancies. {[}32{]} In a recent study 91 Covid-19
patients were analyzed 22 patients with severe disease higher FAR ratio
compare to mild disaese {[}36{]} What does this article add about FAR
ratio in Covid-19 patients: It has been concluded that the FAR ratio,
which is used in diseases such as malignancy, hypertension, and coronary
syndrome as a marker of disease progression, can be used as a mortality
indicator in Covid-19%
\end{abstract}\selectlanguage{ngerman}%



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\verb`far ratio.docx`  available at \url{https://authorea.com/users/427199/articles/533535-predictive-role-of-far-ratio-in-covid-19-patients}

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