Acknowledgements
This work was supported by National Natural Science Foundation of China (82070188 & 81870139 & 81930004), the Foundation for Innovative Research Groups of the National Natural Science Foundation of China (81621001). The authors thank all of the core facilities at Peking University Institute of Hematology for patient care and sample collection. We thank Dr. Li-Ping Guo from Peking University People’s Hospital for excellent transcriptomic data analysis. American Journal Experts (www.journalexperts.com) provided editorial assistance to the authors during the preparation of the manuscript.