Figure 7: Superposition of the closest model to
experiment (blue) onto a structure of target R1156 (green), a homolog of
the SARS-CoV-2 SL5 domain. This target showed substantial experimental
flexibility, and the superposition is to the second highest resolution
cryo-EM map. The GDT_TS is 51%.
The most successful methods used classical RNA modeling methods, and
although deep learning methods did take part, these were not yet
competitive with the more established approaches. No good models were
submitted for the two protein-RNA complexes, and it appears these were
beyond the scope of then available methods. However, newer methods have
appeared since then that may be more capable, for instance (25).