Data Extraction and Management
The same pairs of reviewers independently extracted data on study year, setting and design, study population, intervention(s), comparator(s) and outcome(s). Clinical practices were classified as follows: routine initial diagnostic interventions, initial consultation or therapeutic interventions, and routine post-treatment imaging and follow-up consultations (Table 1). Routine initial and follow-up imaging was defined as that occurring at pre-defined time points and not based on clinical indication.