OVA/SEB allergic peritonitis induces a mixed inflammation response.
To further characterize our model, we analyzed peritoneal levels of IL-4, INFÉ£ and IL-17A, cytokine prototypes from Th1, Th2 and Th17 immune responses. Only IL-4 levels were significantly increased 48h following challenge (Fig. 2A), while INFÉ£ and IL-17A levels increased but not significantly (Fig. 2B-C). These results indicate that the OVA/SEB AP might induce a mixed inflammatory response shifted towards Th2 features.