Study design and population
This prospective, observational study is based on a clinical study
conducted at the between November 2013 and April 2016. The study
participation was open for anyone visiting the hospital interested to
participate in a clinical study.
There were no specific inclusion criteria. Exclusion criteria were
night-work employment and intake of medication with a potential effect
on urine output (such as diuretics, desmopressin, angiotensin-converting
enzyme inhibitors, angiotensin II receptor antagonists and non-steroidal
anti-inflammatory drugs).