Abstract
Background: Many different internal factors have been proven to
influence urine production such as age, weight, and quality of sleep.
External factors such as consumption of caffeine and fluid consumption
have been shown to have an impact on urine production.
Aim: To investigate the impact of movement, physical activity
and position on urine production.
Methods: This prospective observational study was executed at
Ghent University Hospital, Belgium. Study participation was open for
anyone visiting the hospital. Participants collected 1 basic and 2
extended 24-hour urine collections and filled in questionnaires
concerning their general health and physical activity. Urinary levels of
osmolality, sodium and creatinine were determined. Data on movement,
physical activity and position was described.
Results: An increase in body movement leads to a significant
increase in diuresis during daytime, night-time, and 24 hours (p=0,002,
p= <0,001, and p=<0,001, respectively). An increase
in body movement leads to a significant decrease in osmolality during
night-time and 24 hours (p=0,009, and p=0,004, respectively). However,
no significant influence of movement on osmolality was found during
daytime (p=0,12). An increase in body movement leads to a significant
decrease in creatinine during daytime, night-time, and 24 hours
(p=0,001, <0,001, and p=<0,001, respectively). An
increase in body movement leads to a significant increase in sodium
during daytime (p=0,046) but this was statistically significant during
night-time and 24 hours (p=0,32, and p=0,84 respectively).
Conclusion: Our study demonstrates a statistically significant
association of movement, physical activity, and position with urine
production. It would therefore be interesting to explore this
association further with the use of new technology to have more accurate
data. Here lays a potential role for conservative measurements and
lifestyle adaptations in the management of patients with bothersome LUTS
and more precisely nocturia.
Keywords: movement, physical activity, position, urine.