Acknowledgements
We appreciate financial support from National Key R&D Program of China from Ministry of Science and Technology of the People“s Republic of China [grant number 2018YFB1501401], National Natural Science Foundation of China [grant number 31500040, 21978167], and the Natural Science Foundation of Shanghai [grant number 18ZR1420700, 19160745300]. We thank Prof. Hua Zhang and Dr. Huihui Wan in State Key Laboratory of Fine Chemicals, Dalian University of Technology for the metabolic analysis.