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Authorship: D.P. and S.C.P. wrote the editorial.
Declaration of transparency and scientific rigour: This Declaration acknowledges that this paper adheres to the principles for transparent reporting and scientific rigour of preclinical research as stated in the BJP guidelines for Design and Analysis, and as recommended by funding agencies, publishers and other organizations engaged with supporting research.
Funding Acknowledgement: This research was funded by a Medical Research Council project grant (MR/T015845/1) awarded to Dr Simon Pitchford.
Conflict of interest. No author has a conflict of interest to disclose.