Figure captions
Figure 1 . The renin-angiotensin and the kallikrein-kinin
systems in the regulation of blood pressure. The intricate interplay
between these two systems, dependent on the ACE, is the basis of the
control of blood pressure. While the renin-angiotensin mechanism leads
to vasoconstriction and water retention, increasing blood pressure, the
kallikrein-kinin system has opposite effects by promoting vasodilation.
Figure 2. Overview of cloning and expression of ACEIp-coding
synthetic genes in plants and algae. Three main cloning strategies are
used: 1) tandem repeats of a target ACEIp sequence; 2) introduction of
the ACEIp in the hypervariable region of storage proteins, and the 3)
assembly of ACEI polypeptides with others bioactive peptides. These
strategies can be applied in different plant/algae expression platforms,
such as whole transgenic plants/algae, transplastomic plants/algae and
plant/algae cell suspension cultures. The resulting ACEIp-enriched
plants/algae can be used for direct human consumption (direct oral
delivery) or processed by hydrolysis and purified to be used as food
supplements. Images used are from Adobe Stock.